From Hagerstown, Maryland (West)

• I-70 East toward Frederick.
• Merge onto US-340 E / US-15 N via Exit 52B toward Gettysburg.
• Take the MD-180 / Ballenger Creek Pike / MD-351 / Jefferson Pike exit- Exit 11.
• Turn right onto MD-180 / MD-351 / Ballenger Creek Pike / Jefferson Pike. Continue to follow MD-180 / Jefferson Pike.
• End at 5909 Jefferson Pike, Frederick, MD 21703-7031 US.

From Leesburg, Virginia (South)

• US-15 North.
• Take the Mt Zion Road exit.
• Turn left onto Mt Zion Road / Cap Stine Road. Continue to follow Mt Zion Road.
• Turn right onto Jefferson Pike / MD-180.
• End at 5909 Jefferson Pike, Frederick, MD 21703-7031 US.

From Washington, DC (Southeast)

• I-270 North toward Frederick (I-270 becomes US-15 North)
• Take the exit toward Jefferson Street / US-15 / US-340.
• Turn left onto S Jefferson Street / US-340 W.
• Merge right to take the MD-180 exit / MD-351 exit.
• Turn left onto Jefferson Pike / MD-180.
• End at 5909 Jefferson Pike, Frederick, MD 21703-7031 US.

From Baltimore, Maryland (East)

• I-70 West toward Frederick
• Merge onto US-15 North via exit 53B / US-40 W toward Gettysburg.
• Take the exit toward Jefferson Street / US-340 W.
• Merge right to take the MD-180 exit / MD-351 exit.
• Turn left onto Jefferson Pike / MD-180.
• End at 5909 Jefferson Pike, Frederick, MD 21703-7031 US.

From Pennsylvania (North)

• US-15 South toward Frederick
• Take the US-15 S exit / US-340 W toward Leesburg / Charles Town.
• Take the exit toward MD-180 / MD-351.
• Take the MD-180 exit / MD-351.
• Turn left onto Jefferson Pike / MD-180.
• End at 5909 Jefferson Pike, Frederick, MD 21703-7031 US.